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To address these mechanistic differences, researchers propose integrating real-time microenvironmental monitoring technologies (e.g., PET imaging targeting lipid peroxidation products) with multi-omics gene expression profiling to dynamically assess ferroptosis-related pathway activities

Specifically, Ge-Gen-Qin-Lian Decoction (GGQLD) improves intestinal barrier function and reduces inflammation, while Astragalus membranaceus and Lian-Ge granules target insulin signaling and lipid metabolism through multi-pathway modulation (2123)

Both treatments rescued motor coordination (e.g., on beam balance and olfactory function tests) and lowered inflammatory cytokines in the brain, indicating that Mucuna's natural concoction is as efficacious as levodopa in that model [74]

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