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Specifically, certain miRNAs can target and regulate iron metabolism-related proteins or directly inhibit the expression of System Xc and GPX4, thereby promoting ferroptosis (Xu et al., 2021)

In the absence of GPX4 activity, DHODH upregulates CoQH2 production to inhibit ferroptosis (MAO et al., 2021)

2012;7(8):e39373

We hypothesized that CIL, rather than VIL, is the critical factor in perturbation of a circadian clock system in vivo