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Description
17 In contrast, unlocked nucleic acid (UNA) is a flexible RNA mimic that lacks chemical bonds between the ribose rings C2 and C3 atoms

doi: 10.1194/jlr.R067595 Ferr P, and Foufelle F ( 2010 )

This seems very significant in the study of AD because several neurotransmitters are defective in this disease

Also, It reduces PD-1 expression on exhausted T cells, potentially reversing age-related immune decline and improving vaccine responses (315)
