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Description
For Bayesian NMA, specific graphical analysis was completed using the gemtc package in R software v.4.2.1 (R Foundation for Statistical Computing) [15]

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The first and rate-limiting step is catalyzed by the enzyme glutamate-cysteine ligase (GCL), which fuses glutamate and cysteine

A 35% reduction in enzyme activity, in the context of adequate dietary folate from food and a single methylfolate supplement, is usually manageable
