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However, the regulatory effects of C3G on Runx2 vary across experiments
employed high-throughput screening to assay the inhibitory effect of the in-house library of compounds, in order to develop the new generation of IKK inhibitors [196]
These results identify impaired redox homeostasis as a critical driver of neuronal vulnerability in AD and suggest that preserving GSH levels or targeting ferroptotic pathways may offer promising therapeutic strategies for neurodegeneration
Nat Immunol (2007) 8:48796
