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Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles for glutathionylation and other thiol modifications
10.1167/iovs.63.4.27 [DOI] [PMC free article] [PubMed] [Google Scholar] Wang L., Zhang L., Niu Y., Sitia R., Wang C

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It is the first triple-hormone-receptor agonist to reach advanced clinical trials, activating three distinct metabolic pathways that individually would each justify their own drug development program