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These benefits come from chocolates ability to promote production of the vasodilator Nitric Oxide as well as the anandamide within, a cannabinoid compound (like CBD) that binds to receptors in the brain to alter mood and brain activity

279 : 3755937565 Ikarashi M, Takahashi Y, Ishii Y, Nagata T, Asai S and Ishikawa K (2002) Vitamin D3 up-regulated protein 1 (VDUP1) expression in gastrointestinal cancer and its relation to stage of disease

Conversely, agents with neuroprotective properties used in traditional medicine for conditions like forgetfulness and tinnitus, such as Hawthorn Leaf Flavonoids, show efficacy in AD models by reducing oxidative stress and neuroinflammation via the Nrf-2 pathway, indicating common protective mechanisms (Xu et al., 2023)

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