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Given the inflammatory role of mast cells and their presence in the CNS, the effect of ketotifen fumarate, a mast cell stabilizer, was investigated in the context of encephalomyelitis development in mouse model
In this context, Hu et al.s (2023) finding of significantly elevated mtDNAcn in females with PTSD relative to all other groups including female controls suggests that the observed increase may reflect a sex-specific mitochondrial response to trauma
& Demirci, B
