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Pinheiro LC, Oliveira-Paula GH

31,32 L-dopa-associated L-tyrosine depletion

Another study compared changes in ATP levels in axon terminals with or without mitochondria

This also applies to wash in - it will take ~4-5 elimination half-lives of a drug for a constant-rate infusion to reach its final concentration Half-life is mathematically related to many other key pharmacokinetic terms: Various types of half-life are described: t 1/2 describes the rapidity of the distribution phase following drug administration t 1/2 describes the rapidity of the elimination phase occurring after drug distribution equilibrium This only evaluates clearance from plasma, and so is a composite of both excretion from the body (e.g