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SDS-PAGE loading buffer is a harsh treatment that will denature all protein in the sample and restricts the sample to SDS-PAGE analysis only
Testing for MTHFR variants is done for several purposes: Homocysteine Levels and Cardiovascular Risk : Variants in the MTHFR gene can lead to elevated homocysteine levels, a known risk factor for cardiovascular diseases such as heart attack and stroke
In the morning, light activates cell-autonomous photoreceptor Cryptochrome (CRY) and potentiates CRY-TIM interaction which leads to degradation of both proteins
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Among all the regulatory post-translational modifications, FOXO3 also undergoes lysine methylation mediated by Set7/9
