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However, it diminished the expression of fibronectin and the proliferation of rat cardiac fibroblasts [165, 172]

Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review

However, the latter product does contain glycolic acid, an alpha-hydroxy acid (AHA) commonly used in chemical peels.14 This could improve the products effectiveness in reducing hyperpigmentation, but it also raises the risk of it causing irritation

i.e., highly dynamic sets of many rapidly interconverting, structurally distinct conformations, and this structural fuzziness (inherent structural heterogeneity), is often not a limitation but a fundamental aspect of their functions