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Renal and hepatic effects: Long-term or high-dose use has been associated in case reports with adverse effects on kidney and liver function
Although depletion of PMN [14] or IL-1 [15] inhibition showed promising results in animal models and clinical trials have confirmed the efficacy of anti-inflammatory therapies in atherosclerotic cardiovascular diseases (CANTOS[16], COLCOT [17]), no targeted therapies for AAA disease are available so far [18]
For most people, it works best as part of a comprehensive fatloss strategy, not a replacement for one.
Keiser J, Manneck T, Vargas M
