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10.1007/BF01970670 29 ShiJ.ChangX.ZouH.GuJ.YuanY.LiuX.et al (2021)

For those with neurological symptoms, hydroxocobalamin 1 mg is given on alternate days until no further improvement is observed, as recommended by NICE guidance and the product information

Generally, if you are healthy and eating a nutrient-dense diet, your liver can begin rebuilding its stores within 24 to 48 hours after your last dose

Huberman also points to glutamines potential cognitive benefits
