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[DOI] [PubMed] [Google Scholar] 36.Carretero J, Obrador E, Esteve JM, et al

Alzheimers Res Ther (2018) 10:18

SIRT3, SIRT4, and SIRT5 are mitochondrial and can shuttle to the nucleus ( The enzymatic activity of SIRTs is dependent on NAD + as a cofactor and plays an important role in controlling gene expression, DNA repair, metabolism, oxidative stress response, mitochondrial function, and biogenesis
