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Additionally, the inhibition of LRRK2 has been linked to reduced ferroptotic damage via the p62/Keap1/NRF2 axis (132) and teneligliptin, a dipeptidyl peptidase-4 inhibitor, decreases ROS levels and prevents ferroptosis (133)

These forms of regulatory cell death are the main characteristics of the pathogenesis of SIC (49)

This UT3:2Ub model is consistent with the high conservation of ubiquitin sequence and UT3 ridge and cleft sites ( Extended Data Fig

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