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Encourage lifestyle optimization : Sleep, stress management, nutrition quality Support cofactors : Ensure adequate selenium, B vitamins, vitamin C Monitor response : Track subjective improvements (energy, recovery, cognition) and objective markers Adjust as needed : Unlimited consultations to ensure patients benefit from glutathione protocol or to make any adjustments as needed

In astrocytes within the cerebral cortex of AD patients and APP/PS1 double-transgenic AD mice, NOX4 levels of were found to be significantly increased, as were levels of MDA and 4-HNE