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BT from the intestine has been proposed by numerous authors in order to explain sepsis and endotoxemia observed in patients with severe trauma, burns, intestinal obstruction, pancreatitis, and acute liver diseases [4, 58]

These studies aim to map potential mechanisms rather than confirm therapeutic outcomes

While no studies have reported the effect of CPZ ex vivo , this could be an expected response, based on remyelination seen with CPZ treatment cessation, and is in line with findings from Martinez-Pinilla et al., who demonstrated a recovery in cell viability upon cessation of CPZ treatment in vitro (Martnez-Pinilla et al., 2021)

Common signs include: Fatigue Weakness Anemia Pale or yellowish skin Numbness or tingling in the hands and feet Difficulty with balance Glossitis (a swollen, red tongue) Memory or concentration difficulties If you suspect you may have a vitamin B12 deficiency, consult your healthcare provider for appropriate testing and personalized recommendations