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This may be related to the conflicting data on the involvement of Nrf2-dependent processes in macrophage phenotype modification and their coordination with other redox-sensitive signalling systems that regulate inflammation through transcription such factors as NF-B, PPAR, AP-1, and others [18,19]
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Due to their low toxicity, these natural antioxidants have been extensively utilized in the prevention and management of diseases related to oxidative stress (140)
