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Description
We demonstrate that, regardless of the PEG density, knockdown in cells with relatively low glutathione levels can be achieved, as well as the possible effect of steric hindrance of PEG on the availability of the siRNA for cleavage in the intracellular environment

Modernas LNP platform is similarly advanced, with both companies relying on this technology to guarantee high delivery efficiency and low reactogenicity 37,41
In this technique, the point of application is not critical, as molecules will always move to their pI region

Kierszenbaum, A
