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The neuroprotective effects of curcumin are particularly evident in Alzheimers disease, where it addresses multiple pathological features including cholinergic system dysfunction, oxidative damage, and broader nervous system impairment

Finally, it has been shown that the activity of the ubiquitin-proteasome system and the autophagy-lysosomal pathway declines, two of the major catabolic pathways of eukaryotic cells, progressively declines with aging

Cell discovery

The effects of vitamin D3 supplementation on some metabolic and inflammatory markers in diabetic nephropathy patients with marginal status of vitamin D: a randomized double blind placebo controlled clinical trial