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CCK-8 assay revealed that these ferroptosis inhibitors also attenuated PQS-induced cell death, consistent with the results obtained using Fer-1, confirming that PQS induced iron- and ROS-lipid peroxidationmediated ferroptosis (Fig

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Furthermore, biocompatibility assessments indicated minimal hemolytic activity (less than 5%) and no remarkable major pathological alterations within 48 h after administration, implying that PEGPDA@PLGA microspheres are safe and effective antimicrobial therapies
