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Knockdown of HIF-1 significantly increases intracellular ROS and apoptosis levels (Xu, 2018), likely through the upregulation of anti-apoptotic factors or modulation of metabolic pathways

By virtue of these beneficial attributes, chitosan nano-coating, combined with liposomal drug delivery, merges their advantages while reducing their respective limitations

A recent study identified FSP1 as a transcriptional target of Nrf2
