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588,589 In addition, by forming reversible post-translational modifications of Kelch-like ECH-associated protein (Keap) 1, NODEs can lead to nuclear factor (erythroid-derived 2)-like 2 (Nrf2) release from the Keap1/Nrf2 complex, with subsequent Nrf2 translocation to the nucleus and the induction of an array of antioxidant genes
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It also supports normal energy-yielding metabolism and helps reduce tiredness and fatigue
An increase was seen when injected intraperitoneally but to a lesser extent [145]
