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[7] [9] Patients with a history of oxalate nephrolithiasis (kidney stones) or hyperoxaluria should avoid high-dose vitamin C administration, as ascorbic acid is metabolized to oxalate, which may precipitate stone formation or exacerbate renal impairment

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Structural Features MT-1 retains the 13-amino acid chain structure of -MSH Two substitutions within the structure of MT-1 increase its metabolic stability and half-life as compared to natural -MSH

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