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Description
Intriguingly, recent studies examining mutant SOD1 suggest that the aggregation of this protein may be due to a lack of proper metalation

These organisms have been modified through gene editing to alter their original metabolic pathways, enabling low-cost production of target active substances ( Saccharomyces cerevisiae cells while blocking the sterol branch pathway, which resulted in a significant increase in the content of the precursor mevalonate in the mutant strain (Paddon et al., 2013

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