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Which upregulate genes for fat oxidation (CPT1, ACOX1) and mitochondrial biogenesis (PGC-1)

This shift provides information about the local environments polarity, dynamics, and rigidity, making it useful for monitoring protein stability, conformational changes, and ligand binding

This process ultimately leads to cell lysis and the release of a large number of inflammatory factors (such as IL-1 and IL-18) into the surrounding environment [178]

Experimental investigations have reported effects on VEGFR2 phosphorylation, focal adhesion kinase (FAK) activation, ERK1/2 signaling, and nitric oxide-associated regulatory pathways