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Additionally, the establishment of hypoxic tumor microenvironments and accumulation of hypoxia-inducible factor (HIF-1) have been mechanisms that resist radiotherapy and promote CRC survival (108)
Current prophylactic treatments targeting mitochondrial function and energy metabolism include riboflavin, coenzyme Q10, alpha-lipoic acid, and ketogenic ketones
Critical roles of protein disulfide isomerases in balancing proteostasis in the nervous system
Pipecolic acid mitigates ferroptosis in diabetic retinopathy by regulating Gpx4-Yap signaling
