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A prior study identified six putative phosphorylation sites (S155, T189, T216, S246, S284, T292) within ArfGAP1 by mass spectrometry yet no quantitative analysis was provided, and it was unclear which LRRK2 variants were used in these assays, including whether comparison to a kinase-inactive LRRK2 negative control was included (Xiong et al., 2012)
Reducing frequency and pausing other actives usually resolves the breakouts within a month
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