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Amit Mishra, Indian Institute of Technology Jodhpur, India

A retrospective analysis of a national medical records database (2017/2018, n = 473 patients) revealed that 40% of women with IPTB delivered within 48 h, justifying the initial NAC iv -infusion for the severe IPTB subgroup to maximize efficacy, due to NACs rapid placental transfer

Although efforts were made to enhance transparency in the literature selection and to prioritize high-quality evidence, the absence of formal risk-of-bias assessment and quantitative synthesis should be considered when interpreting the conclusions