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Contraindications Vitamin B12 injection is contraindicated in pregnant and lactating women, liver disease, kidney disease, infection, iron deficiency, folic acid deficiency, the patient undergoing treatment that has a direct effect on bone marrow, an allergy to medication, vitamin, preservative or cobalt

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Thats a mechanistically different target than NSAIDs (nonsteroidal anti-inflammatory drugs), or corticosteroids, which partly explains why the compound has attracted interest in cases where conventional anti-inflammatory approaches have failed or created downstream problems
