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[DOI] [PubMed] [Google Scholar] 157.Witte S., Villalba M., Bi K., Liu Y., Isakov N., Altman A

Fitoterapia 82(4):513523

The peptide has also demonstrated anti-aggression effects, reducing physical attacks by 5-fold in stimulated environments at very low doses

Together, our observations that a small molecule NNMT inhibitor can increase NAD + and SAM concentrations in differentiated adipocytes and reduce adiposity in DIO mice, suggest that treatment with an NNMT inhibitor effectively reverses obesity via modulation of the NAD + salvage and SAM-mediated (e.g., polyamine flux) pathways to regulate energy expenditure in the adipose tissue