glutathione and lung function NRF2 supports non-small cell cancer growth independently of CBP/p300-enhanced synthesis | EMBO Reports Natural Compounds and Glutathione: Beyond
Description
GSH depletion in response to oxidants has been widely reported, and linked to cell death [116]
ROS are produced by multiple intrinsic mechanisms, and ROS come in a variety of forms, including radical (hydroxyl, superoxide, etc.) or non-radical (hydrogen peroxide, singlet oxygen, etc.) [25]
PubMed Thomas, M.K., Nikooienejad, A., Bray, R., Cui, X., Wilson, J., Duffin, K., et al
Glycolytic NAD-dependent GAPDH is a cytosolic enzyme that is also partly associated with mitochondria and the nucleus (Gieg et al., 2003
