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As mentioned for topical corticosteroids, topical tacrolimus also has an evident result, especially on the face, and it could be an alternative to topical corticosteroids in some cases, such as acneiform eruption, or when topical corticosteroids show no sign of recovery on the face ( Phototherapy, which includes ultraviolet A and B, is an efficient way to induce repigmentation in vitiligo owing to its ability to produce melanin and induce the differentiation of melanocytes ( Dexamethasone (2.510) mg is an oral corticosteroid used in vitiligo treatment as an immunosuppressant and anti-inflammatory agent, and when administered twice weekly, it can prevent the progression and spread of disease (Dellatorre et al., 2020)

doi: 10.1016/j.biopha.2022.113810 58 MacchioneI

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