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doi: 10.3389/fnut.2026.1778396 Received 30 December 2025 Revised 02 March 2026 Accepted 17 March 2026 Published 27 March 2026 Volume 13 - 2026 Edited by Fernanda Barbisan, Federal University of Santa Maria, Brazil Reviewed by Yesica Maria Rodriguez Corts, National Autonomous University of Mexico, Mexico Cansu Koc, Uludag University Faculty of Medicine, Trkiye Wipawee Thukhammee, Khon Kaen University, Thailand Updates Copyright 2026 Bu, Zhang, Qi and Xu

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sativa may lower fasting blood sugar levels by an average of 17.8 mg/dL ( The same reviews also report a drop of around 0.7% in hemoglobin A1C, which suggests improved blood sugar control ( Experts believe that Nigella sativa may be able to increase the secretion of insulin, the hormone responsible for transporting sugar from your blood into your cells

Severe cellular energy stress may therefore impair SAM production, although plasma values must be interpreted in clinical context