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ROS reactive oxygen species LPO lipid peroxidation MPO myeloperoxidase Bax Bcl-2-associated X Bcl-2 B-cell lymphoma-2 Fu Furan CCl4 carbon tetrachloride DEHP Di (2-ethylhexyl) phthalate PbAc lead acetate NDEA N-nitrosodiethylamine LPS lipopolysaccharide D-GalN D-Galactosamine I/R Ischemia-reperfusion NiONPs Nickel oxide nanoparticles PA palmitic acid NASH nonalcoholic steatohepatitis OA oleic acid XO xanthine oxidase CTSB cathepsin B AMPK AMP-activated protein kinase FAS fatty acid synthase JAK2 Janus kinase 2 STAT3 signal transducer and activator of transcription 3 TC total cholesterol TG triglyceride ECM extracellular matrix HSCs hepatic stellate cells BDL bile duct ligation MMP2/8 matrix metalloproteinase 2/8 TIMP1 tissue inhibitors of metalloproteinase 1 iNOS inducible nitric oxide synthase NO nitric oxide ERK extracellular signal-regulated kinase H2O2 hydrogen peroxide TLR4 Toll-like receptor4 DDC 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine MAPK mitogen-activated protein kinases IFN-I type I interferon miRNAs microRNA SHP-1 Src homology 2 domain-containing protein tyrosine phosphatase 1 EVs extracellular vesicles EMT epithelial-mesenchymal transition SOR sorafenib DOX doxorubicin PTX paclitaxel CDDP cisplatin 5-FU 5-Fluorouracil CHR chrysin HPLC-MS/MS high-performance liquid chromatography-tandem mass spectrometry UPLC-MS/MS ultra-performance liquid chromatography-tandem mass spectrometry DEN diethylnitrosamine References 1 AhlmannM.HempelG

In conclusion, PQQ has a protective effect on the premature senescence model of HEI-OC1 auditory cells and is associated with the SIRT1/PGC-1 signaling pathway, mitochondrial structure, and mitochondrial respiratory capacity

In a research performed by Stortz and Marangoni (2014), thixotropic EC oleogels were developed to replace petrolatum as a structuring agent in cosmetics

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