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Their mode of action may not be directly related to an AT mechanism but may involve other effects, as some of them (including PBN) were shown to release NO (nitric oxide), which can inhibit ROS-producing enzymatic activity

FIGURE 3 The pharmacokinetic properties of urinary-excreted phytochemicals play a vital role in their effectiveness in managing IC

Fahey JW, Haristoy X, Dolan PM, et al

Supporting your body with bioavailable nutrients and a liver-conscious lifestyle can help maintain your internal defenses
