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Urine protein decreased from more than 6 g/day to about 1 g/day, Serum creatinine levels returned to normal as well as serological analysis showed a marked reduction in anti-double-stranded DNA antibodies

RRM2 is an enzyme playing a crucial role in DNA synthesis and repair via deoxyribonucleotide production (72)

Additionally, we examined pertinent topics within this field, including clinical evidence demonstrating an increased risk of vitamin B12 deficiency, potential mechanisms elucidating this elevated risk, and the risk factors and consequences of vitamin B12 deficiency in patients with T2D receiving metformin therapy