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CONCLUSION While the development of antiobesity drugs continues to look challenging, researchers retain the hope that effective and safe medications might be on the horizon

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If the abovementioned is occurring, it could mean that IGF-1 administration could also lower glucose levels by suppressing hepatic gluconeogenesis, as well as improving insulin signalling in this organ, leading to IGFBP-1 suppression and overall improvement of the IGF-1/GH/insulin axis

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