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These modifications stabilize the molecular structure, allowing it to mimic the amphipathic alpha-helix of the native hormone

5-Hydroxytryptophan (5HTP) is an amino acid involved in converting the amino acid L Tryptophan to Serotonin, which is a neurotransmitter or "messenger brain chemical" associated with the regulation of sleep
All subjects also had a positive [18F]FDG PET/CT scan within 1month prior to the [18F]FSPG PET scan