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The role of interactions between tumor cells and components of the stroma, immune cells, or endothelial cells can influence the efficiency of metastasis, resulting in reduction, persistence, or progressive metastasis
A 2012 systematic review and meta-analysis, along with a 2013 controlled clinical trial, showed that ALA is an effective drug in the treatment of diabetic neuropathy, which affects about 50 percent of people with diabetes

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Biochem J 204(1):2530
