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On the contrary, there are no data to suggest that CRP is the direct cause of any disease, whereas CRP infused in relatively healthy human adults does not trigger any significant clinical, hematologic, coagulative, or biochemical alterations, or any increase in proinflammatory cytokines or acute phase proteins [113]

The biochemical changes, the surface hydrophobicity, and the crosslinking formation caused by oxidation could be reflected by di-tyrosine and disulfide bonds 4 (90)

Biomolecules 9 , 273 (2019)

10.1002/adhm.202102038 254 ZhaoY.FengX.ChenY.SelfridgeJ
