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This Figure shows conversion of glutamine to glutamate by PAG, followed by a process similar to that occurring in the MAS, with the only exception that the glutamate molecule involved does not originate in the cytosol, but from PAG-activated de-amidation of glutamine in the intermembranaceus space of the mitochondrion

These secondary structures are organized in two domains: an amino-terminal Rossmann fold-like domain (catalytic domain) that contains 14 helical elements and 13 -strands (113) and a C-terminal left-handed -helix (LH) domain that consists of 17 -strands (1430) (Zhang et al., 2022b)

Moors TE, Hoozemans JJ, Ingrassia A, Beccari T, Parnetti L, Chartier-Harlin MC, et al

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