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KORs are highly expressed in the prefrontal cortex, nucleus accumbens, amygdala, and hippocampus, where they help regulate dopamine levels, modulate glutamate transmission, and maintain GABAergic inhibition [57]
[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Plichta JK, Radek KA
Both were ultimately connected to ventilators
Nasal delivery supports direct central nervous system access, making it useful for studying cognitive modulation without injectable protocols
