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Description
8:e1042
Repairs: Antioxidant blend neutralizes damaging blue light and free radicals, reducing redness, calming irritation, and protecting against signs of premature aging
doi: 10.3389/fragi.2022.931331 85
After mutation of the PAZ RNA-binding pocket (F294A, Y311A), trigger variants with longer internal loops induced binding and polyubiquitylation no better than did the seed-only variant, supporting the idea that together, trigger-specific RNA trajectory and binding of the vacated PAZ pocket substantially contribute to ZSWIM8 selectivity for TDMD substrates
