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Management strategies for hyperemesis

10.1038/ijos.2017.35 159

Severe hyperglycaemia may induce glucotoxicity in selective neurons involved in cognitive processing, with hippocampal neurons having been identified as particularly vulnerable to hyperglycaemia, and with proposed mechanisms including mitochondrial dysfunction and inflammatory responses [35]

A dose that produces an effect in a mouse does not scale linearly to a human by body weight, and the research doses in this protocol are practitioner-derived conventions, not figures validated against human outcomes
