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Contrave Mechanism of action Contrave consists of two drugs: naltrexone sustained release (SR) and bupropion SR

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Vitamin B-12 aids the development and maintenance of what is known within medical lingo as the myelin sheath. This is a protective layer formed around the nerves, so when deficiency occurs, this layer can become damaged

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NG239 Vitamin B12 deficiency in over 16s Evidence review C: diagnostic tests

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