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The design of novel therapeutic agents such as monoclonal antibodies (mAbs), stem cells and genes is currently under way and clinical trials have been attempted, however, the therapeutic efficacy has been greatly limited by the fact that large molecular agents cannot penetrate the blood-brain barrier (BBB)
A 2013 study linked low vitamin B12 and folate levels with an increased risk of age-related macular degeneration ( Although the reduction in risk cant be attributed to vitamin B12 only, it does suggest that getting enough may be important
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