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If you suffer from vitamin B12 deficiency, you may notice that you are losing muscle strength or mass

Research has shown that between 50% and 98% of injected vitamin B12 is found in the urine 48 hours after it is administered

Cui Y, Yang D, Wang W, Zhang L, Liu H, Ma S, Guo W, Yao M, Zhang K, Li W (2020) Nicotinamide N-methyltransferase decreases 5-fluorouracil sensitivity in human esophageal squamous cell carcinoma through metabolic reprogramming and promoting the Warburg effect

Theres no clear understanding of why adequate levels of B12 are associated with a reduced risk of obesity, but there are a few theories 9-11 : B12 may influence how the body stores fat B12 is required for proper muscle protein, and low levels could interfere with recovery Insufficient B12 impairs red blood cell production and interferes with oxygen delivery to muscles Key takeaway: There is some evidence linking low B12 levels to a higher risk of obesity in children, adolescents, and adults, but the evidence is too weak to confirm a relationship