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When a mouse carrying a xenograft produced by a mixture of HCTT16 WT and HCT116 p53 -/ p53 - is treated with an anti VEGF antibody an initial shrinkage of the tumour occurs as most of the WT-hypoxia sensitive cells undergo apoptosis

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Complete hydrolysis of a protein or peptide, followed by amino acid analysis establishes its gross composition, but does not provide any bonding sequence information

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Atg5 fl/fl ), referred to as WT

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