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When GLP- 1 receptor agonists are used to treat T2DM, there is also a noticeable reduction in post-meal glycemic fluctuations due to their short-term, transient effect on slowing gastric emptying

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2.3 Molecular docking analysis Three-dimensional (3D) crystal structures of JAK1 (PDB ID: 6AAH), JAK2 (PDB ID: 7F7W), and STAT3 (PDB ID: 6NUQ) were obtained from the Research Collaboratory for Structural Bioinformatics (RCSB) Protein Data Bank ( The molecular structure of CDN was retrieved from the PubChem database ( To prepare the proteins for docking, water molecules and co-crystallized ligands were removed from the protein structures